Week Five Spreads

The favorites are listed in Bold with the number of points they are favored by after their name.
Date Kickoff Time (CT) Visitor Home
10/02/20257:15 PMSan FranciscoL.A. Rams
10/05/20258:30 AMMinnesotaCleveland
10/05/202512:00 PMLas VegasIndianapolis
10/05/202512:00 PMN.Y. GiantsNew Orleans
10/05/202512:00 PMDallasN.Y. Jets
10/05/202512:00 PMDenverPhiladelphia
10/05/202512:00 PMMiamiCarolina
10/05/202512:00 PMHoustonBaltimore
10/05/20253:05 PMTennesseeArizona
10/05/20253:05 PMTampa BaySeattle
10/05/20253:25 PMDetroitCincinnati
10/05/20253:25 PMWashingtonL.A. Chargers
10/05/20257:20 PMNew EnglandBuffalo
10/06/20257:15 PMKansas CityJacksonville