Week Eighteen Spreads
The favorites are listed in
Bold with the number of points they are favored by after their name.
| Date |
Kickoff Time (CT) |
Visitor |
Home |
| 01/04/2025 | 3:30 PM | Cleveland | Baltimore -17½ |
| 01/04/2025 | 7:00 PM | Cincinnati -1½ | Pittsburgh |
| 01/05/2025 | 12:00 PM | Carolina | Atlanta -7½ |
| 01/05/2025 | 12:00 PM | Washington -4½ | Dallas |
| 01/05/2025 | 12:00 PM | Chicago | Green Bay -9½ |
| 01/05/2025 | 12:00 PM | Houston | Tennessee -½ |
| 01/05/2025 | 12:00 PM | Jacksonville | Indianapolis -4½ |
| 01/05/2025 | 12:00 PM | Buffalo -2½ | New England |
| 01/05/2025 | 12:00 PM | N.Y. Giants | Philadelphia -2½ |
| 01/05/2025 | 12:00 PM | New Orleans | Tampa Bay -13½ |
| 01/05/2025 | 3:25 PM | Kansas City | Denver -10½ |
| 01/05/2025 | 3:25 PM | L.A. Chargers -4½ | Las Vegas |
| 01/05/2025 | 3:25 PM | Seattle -6½ | L.A. Rams |
| 01/05/2025 | 3:25 PM | Miami -½ | N.Y. Jets |
| 01/05/2025 | 3:25 PM | San Francisco | Arizona -4½ |
| 01/05/2025 | 7:20 PM | Minnesota | Detroit -3½ |