Week One Spreads

The favorites are listed in Bold with the number of points they are favored by after their name.
Date Kickoff Time (CT) Visitor Home
09/04/20257:20 PMDallasPhiladelphia -7½
09/05/20257:00 PMKansas City -3½L.A. Chargers
09/07/202512:00 PMTampa Bay -2½Atlanta
09/07/202512:00 PMCincinnati -4½Cleveland
09/07/202512:00 PMMiamiIndianapolis -½
09/07/202512:00 PMLas VegasNew England -2½
09/07/202512:00 PMArizona -6½New Orleans
09/07/202512:00 PMPittsburgh -2½N.Y. Jets
09/07/202512:00 PMN.Y. GiantsWashington -6½
09/07/202512:00 PMCarolinaJacksonville -3½
09/07/20253:05 PMTennesseeDenver -7½
09/07/20253:05 PMSan Francisco -2½Seattle
09/07/20253:25 PMDetroitGreen Bay -2½
09/07/20253:25 PMHoustonL.A. Rams -2½
09/07/20257:20 PMBaltimore -1½Buffalo
09/08/20257:15 PMMinnesota -1½Chicago